MobileManiBench: Simplifying Model Verification for Mobile Manipulation

Vision-language-action models have advanced robotic manipulation but remain constrained by reliance on the large, teleoperation-collected datasets dominated by the static, tabletop scenes. We propose a simulation-first framework to verify VLA architectures before real-world deployment and introduce MobileManiBench, a large-scale benchmark for mobile-based robotic manipulation. Built on NVIDIA Isaac Sim and powered by reinforcement learning, our pipeline autonomously generates diverse manipulation trajectories with rich annotations (language instructions, multi-view RGB-depth-segmentation images, synchronized object/robot states and actions). MobileManiBench features 2 mobile platforms (parallel-gripper and dexterous-hand robots), 2 synchronized cameras (head and right wrist), 630 objects in 20 categories, 5 skills (open, close, pull, push, pick) with over 100 tasks performed in 100 realistic scenes, yielding 300K trajectories. This design enables controlled, scalable studies of robot embodiments, sensing modalities, and policy architectures, accelerating research on data efficiency and generalization. We benchmark representative VLA models and report insights into perception, reasoning, and control in complex simulated environments.

Reward-free Alignment for Conflicting Objectives

Direct alignment methods are increasingly used to align large language models (LLMs) with human preferences. However, many real-world alignment problems involve multiple conflicting objectives, where naive aggregation of preferences can lead to unstable training and poor trade-offs. In particular, weighted loss methods may fail to identify update directions that simultaneously improve all objectives, and existing multi-objective approaches often rely on explicit reward models, introducing additional complexity and distorting user-specified preferences. The contributions of this paper are two-fold. First, we propose a Reward-free Alignment framework for Conflicted Objectives (RACO) that directly leverages pairwise preference data and resolves gradient conflicts via a novel clipped variant of conflict-averse gradient descent. We provide convergence guarantees to Pareto-critical points that respect user-specified objective weights, and further show that clipping can strictly improve convergence rate in the two-objective setting. Second, we improve our method using some heuristics and conduct experiments to demonstrate the compatibility of the proposed framework for LLM alignment. Both qualitative and quantitative evaluations on multi-objective summarization and safety alignment tasks across multiple LLM families (Qwen 3, Llama 3, Gemma 3) show that our method consistently achieves better Pareto trade-offs compared to existing multi-objective alignment baselines.

LongVPO: From Anchored Cues to Self-Reasoning for Long-Form Video Preference Optimization

We present LongVPO, a novel two-stage Direct Preference Optimization framework that enables short-context vision-language models to robustly understand ultra-long videos without any long-video annotations. In Stage 1, we synthesize preference triples by anchoring questions to individual short clips, interleaving them with distractors, and applying visual-similarity and question-specificity filtering to mitigate positional bias and ensure unambiguous supervision. We also approximate the reference model's scoring over long contexts by evaluating only the anchor clip, reducing computational overhead. In Stage 2, we employ a recursive captioning pipeline on long videos to generate scene-level metadata, then use a large language model to craft multi-segment reasoning queries and dispreferred responses, aligning the model's preferences through multi-segment reasoning tasks. With only 16K synthetic examples and no costly human labels, LongVPO outperforms the state-of-the-art open-source models on multiple long-video benchmarks, while maintaining strong short-video performance (e.g., on MVBench), offering a scalable paradigm for efficient long-form video understanding.

RareAlert: Aligning heterogeneous large language model reasoning for early rare disease risk screening

Missed and delayed diagnosis remains a major challenge in rare disease care. At the initial clinical encounters, physicians assess rare disease risk using only limited information under high uncertainty. When high-risk patients are not recognised at this stage, targeted diagnostic testing is often not initiated, resulting in missed diagnosis. Existing primary care triage processes are structurally insufficient to reliably identify patients with rare diseases at initial clinical presentation and universal screening is needed to reduce diagnostic delay. Here we present RareAlert, an early screening system which predict patient-level rare disease risk from routinely available primary-visit information. RareAlert integrates reasoning generated by ten LLMs, calibrates and weights these signals using machine learning, and distils the aligned reasoning into a single locally deployable model. To develop and evaluate RareAlert, we curated RareBench, a real-world dataset of 158,666 cases covering 33 Orphanet disease categories and more than 7,000 rare conditions, including both rare and non-rare presentations. The results showed that rare disease identification can be reconceptualised as a universal uncertainty resolution process applied to the general patient population. On an independent test set, RareAlert, a Qwen3-4B based model trained with calibrated reasoning signals, achieved an AUC of 0.917, outperforming the best machine learning ensemble and all evaluated LLMs, including GPT-5, DeepSeek-R1, Claude-3.7-Sonnet, o3-mini, Gemini-2.5-Pro, and Qwen3-235B. These findings demonstrate the diversity in LLM medical reasoning and the effectiveness of aligning such reasoning in highly uncertain clinical tasks. By incorporating calibrated reasoning into a single model, RareAlert enables accurate, privacy-preserving, and scalable rare disease risk screening suitable for large-scale local deployment.

Persistent Sheaf Laplacian Analysis of Protein Stability and Solubility Changes upon Mutation

Genetic mutations frequently disrupt protein structure, stability, and solubility, acting as primary drivers for a wide spectrum of diseases. Despite the critical importance of these molecular alterations, existing computational models often lack interpretability, and fail to integrate essential physicochemical interaction. To overcome these limitations, we propose SheafLapNet, a unified predictive framework grounded in the mathematical theory of Topological Deep Learning (TDL) and Persistent Sheaf Laplacian (PSL). Unlike standard Topological Data Analysis (TDA) tools such as persistent homology, which are often insensitive to heterogeneous information, PSL explicitly encodes specific physical and chemical information such as partial charges directly into the topological analysis. SheafLapNet synergizes these sheaf-theoretic invariants with advanced protein transformer features and auxiliary physical descriptors to capture intrinsic molecular interactions in a multiscale and mechanistic manner. To validate our framework, we employ rigorous benchmarks for both regression and classification tasks. For stability prediction, we utilize the comprehensive S2648 and S350 datasets. For solubility prediction, we employ the PON-Sol2 dataset, which provides annotations for increased, decreased, or neutral solubility changes. By integrating these multi-perspective features, SheafLapNet achieves state-of-the-art performance across these diverse benchmarks, demonstrating that sheaf-theoretic modeling significantly enhances both interpretability and generalizability in predicting mutation-induced structural and functional changes.

SfMamba: Efficient Source-Free Domain Adaptation via Selective Scan Modeling

Source-free domain adaptation (SFDA) tackles the critical challenge of adapting source-pretrained models to unlabeled target domains without access to source data, overcoming data privacy and storage limitations in real-world applications. However, existing SFDA approaches struggle with the trade-off between perception field and computational efficiency in domain-invariant feature learning. Recently, Mamba has offered a promising solution through its selective scan mechanism, which enables long-range dependency modeling with linear complexity. However, the Visual Mamba (i.e., VMamba) remains limited in capturing channel-wise frequency characteristics critical for domain alignment and maintaining spatial robustness under significant domain shifts. To address these, we propose a framework called SfMamba to fully explore the stable dependency in source-free model transfer. SfMamba introduces Channel-wise Visual State-Space block that enables channel-sequence scanning for domain-invariant feature extraction. In addition, SfMamba involves a Semantic-Consistent Shuffle strategy that disrupts background patch sequences in 2D selective scan while preserving prediction consistency to mitigate error accumulation. Comprehensive evaluations across multiple benchmarks show that SfMamba achieves consistently stronger performance than existing methods while maintaining favorable parameter efficiency, offering a practical solution for SFDA. Our code is available at https://github.com/chenxi52/SfMamba.

Knowledge Distillation for LLM-Based Human Activity Recognition in Homes

Human Activity Recognition (HAR) is a central problem for context-aware applications, especially for smart homes and assisted living. A few very recent studies have shown that Large Language Models (LLMs) can be used for HAR at home, reaching high performance and addressing key challenges. In this paper, we provide new experimental results regarding the use of LLMs for HAR, on two state-of-the-art datasets. More specifically, we show how recognition performance evolves depending on the size of the LLM used. Moreover, we experiment on the use of knowledge distillation techniques to fine-tune smaller LLMs with HAR reasoning examples generated by larger LLMs. We show that such fine-tuned models can perform almost as well as the largest LLMs, while having 50 times less parameters.

On the Limitations of Rank-One Model Editing in Answering Multi-hop Questions

Recent advances in Knowledge Editing (KE), particularly Rank-One Model Editing (ROME), show superior efficiency over fine-tuning and in-context learning for updating single-hop facts in transformers. However, these methods face significant challenges when applied to multi-hop reasoning tasks requiring knowledge chaining. In this work, we study the effect of editing knowledge with ROME on different layer depths and identify three key failure modes. First, the "hopping-too-late" problem occurs as later layers lack access to necessary intermediate representations. Second, generalization ability deteriorates sharply when editing later layers. Third, the model overfits to edited knowledge, incorrectly prioritizing edited-hop answers regardless of context. To mitigate the issues of "hopping-too-late" and generalisation decay, we propose Redundant Editing, a simple yet effective strategy that enhances multi-hop reasoning. Our experiments demonstrate that this approach can improve accuracy on 2-hop questions by at least 15.5 percentage points, representing a 96% increase over the previous single-edit strategy, while trading off some specificity and language naturalness.

All That Glisters Is Not Gold: A Benchmark for Reference-Free Counterfactual Financial Misinformation Detection

We introduce RFC Bench, a benchmark for evaluating large language models on financial misinformation under realistic news. RFC Bench operates at the paragraph level and captures the contextual complexity of financial news where meaning emerges from dispersed cues. The benchmark defines two complementary tasks: reference free misinformation detection and comparison based diagnosis using paired original perturbed inputs. Experiments reveal a consistent pattern: performance is substantially stronger when comparative context is available, while reference free settings expose significant weaknesses, including unstable predictions and elevated invalid outputs. These results indicate that current models struggle to maintain coherent belief states without external grounding. By highlighting this gap, RFC Bench provides a structured testbed for studying reference free reasoning and advancing more reliable financial misinformation detection in real world settings.

Learning to Diagnose and Correct Moral Errors: Towards Enhancing Moral Sensitivity in Large Language Models

Moral sensitivity is fundamental to human moral competence, as it guides individuals in regulating everyday behavior. Although many approaches seek to align large language models (LLMs) with human moral values, how to enable them morally sensitive has been extremely challenging. In this paper, we take a step toward answering the question: how can we enhance moral sensitivity in LLMs? Specifically, we propose two pragmatic inference methods that faciliate LLMs to diagnose morally benign and hazardous input and correct moral errors, whereby enhancing LLMs' moral sensitivity. A central strength of our pragmatic inference methods is their unified perspective: instead of modeling moral discourses across semantically diverse and complex surface forms, they offer a principled perspective for designing pragmatic inference procedures grounded in their inferential loads. Empirical evidence demonstrates that our pragmatic methods can enhance moral sensitivity in LLMs and achieves strong performance on representative morality-relevant benchmarks.